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Reducing neutrophils or inhibiting NETs improves wound healing in sickle cell disease.

This study revealed that basement membrane dynamics are crucial to hair follicle development, influencing progenitor cell behavior and cell division patterns in developing mouse hair follicles.

This study observed that gender-affirming hormone therapy differentially affects metabolism in mice, with the specific metabolic impacts dependent on the type of hormonal treatment used.

In this study, researchers described protocols using C3H/HeJ mice to reliably induce alopecia areata through full-thickness skin grafts or adoptive transfer of cultured lymphoid cells, offering valuable models for studying the disease and testing new drug therapies.

This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.

This study describes a new method using ImageJ to quantitatively assess hair loss in mice with alopecia areata, offering a more precise and reproducible alternative to traditional visual scoring systems by employing image-based analysis techniques.

A new image-based method improves accuracy in measuring hair loss in mice.

This study established a mouse model of atopic dermatitis with overgrowth of Malassezia globosa using olive oil as a vehicle, which caused severe lesions and hair follicle damage.

This study established a model using nude mice to successfully graft human scalp skin, maintaining hair follicle growth and skin integrity for at least two months, which may aid preclinical research.

In a mouse model of peripheral vascular disease, this study found that recombinant thymosin β4 treatment increased expression levels of certain proteins, promoting angiogenesis.

This study observed that Tudor-SN protein may play a significant role in the immune system and that polyamines can influence hair growth in a mouse model.

This study explored the effects of a common Hutchinson-Gilford progeria syndrome mutation in an inducible mouse model, revealing skin abnormalities similar to those in affected patients.

Cyclosporine starts hair growth faster, while minoxidil makes it last longer.

This review highlights that genetically engineered mouse models are valuable for studying melanoma development and progression by mimicking human skin biology, revealing key signaling pathways and molecular mechanisms that contribute to melanoma heterogeneity and offering insights into potential therapeutic targets.

In this study, activated PRP injections appeared to promote hair growth in AGA-affected scalp skin transplanted onto mice, compared to non-activated PRP.

This study reports that C3H/HeJ mice and DEBR rats serve as effective models for screening potential treatments for human alopecia areata, despite certain challenges in predictability and cost.

This study successfully developed a reproducible mouse model demonstrating fetal scarless wound healing, which may provide insights for minimizing scarring in adults.

This study concluded that rapid thawing during cryoablation enhances neutrophil and lymphocyte infiltration, increases oxidative stress, and induces cell death, resulting in more substantial tissue damage in mice compared to natural thawing.

This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.

In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.

This study details the presence of two types of cysts in rhino mouse skin, with utricles derived from hair canals and deeper cysts from hair root sheath epithelium.

This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.

This review revisits the mechanisms of wound induced hair follicle neogenesis in mice and concludes that the process involves canonical WNT signaling activated by Fgf9 from γδ T cells, but more research is needed to fully understand its cellular bases.

This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.

This study developed a kidney-specific knockout mouse model lacking the Flcn gene, which recapitulates human Birt-Hogg-Dubé kidney tumorigenesis and shows that mTOR pathway inhibition with rapamycin can suppress tumor growth.

This study suggests that progesterone has both THP/GABAA-dependent and independent anticonvulsive effects in a hippocampal-kindled mouse model.

This study found that in a transgenic mouse model, β-HPV infection led to increased skin thickness and proliferation of specific keratinocyte stem cells, which may contribute to squamous cell carcinoma development.

This study in mice found that butin, a component of Vernonia anthelmintica, increased melanin production and related proteins while reducing oxidative stress markers in a model of hydroquinone-induced vitiligo, suggesting support for its traditional use against this condition.

This study found that in SAMP8 mice, phenotypic changes in outer hair cells or the stria vascularis, possibly due to oxidative deficiencies, may predict variability in age-related hearing loss before outer hair cell loss occurs.