July 2026 in “Pharmaciana” This study found that the optimal characteristics for ulin seed oil extraction are fresh, mature, and resinous seeds, and that FTIR spectrophotometry with PCA can effectively detect adulteration of the oil, particularly at certain wavenumbers like 1745 cm⁻¹.
This study aimed to develop a natural hair serum using ingredients like myroxylon balsam oil, flaxseed, almond oil, and Vitamin E, which are noted for benefits such as reducing dandruff, enhancing shine, calming the scalp, and promoting hair growth.
January 2024 in “IFMBE proceedings”
128 citations
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July 2009 in “International Journal of Pharmaceutics” This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.
November 2024 in “Journal of Cosmetic Dermatology” This study found that valproic acid-loaded microemulsion formulations enhanced skin penetration pathways in guinea pigs compared to an aqueous solution, with composition elements like oil content and surfactant ratios significantly affecting drug delivery performance.
January 2024 in “EduChemia (Jurnal Kimia dan Pendidikan)” This study found that an oleogel combining watermelon rind extract and orange peel essential oil led to 100% hair growth in male DDY mice, highlighting these extracts as potential nutrients for treating hair loss.
4 citations
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January 2011 This thesis explores the synthesis and antiproliferative properties of phenylpropanoid sucrose esters, noting the absence of synthetic methods for most of this compound class due to their structural complexity.
October 2025 in “International Journal of Cosmetic Science” This study found that longer-chain cationic surfactants like BTMC provided superior hair conditioning by reducing combing forces, but did not reverse oxidative hair damage, emphasizing the role of molecular structure in surfactant performance.
6 citations
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November 1960 in “Experimental Biology and Medicine” In this study, despite morphological differences in the hair growth cycle stages, the lipid composition of the epidermis and dermis showed no significant variation, though water content and cholesterol levels differed between these skin layers.
31 citations
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January 2008 in “Gynecological endocrinology” In this study, two different estroprogestin treatments significantly improved skin conditions and decreased androgen levels in hyperandrogenic women, with EE/DRSP showing more pronounced hormonal changes and skin improvements compared to EE/CMA.
8 citations
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January 1968 This study found that high concentrations of dimethyl sulfoxide are needed to cause significant swelling in hair fibers, though the swelling is reversible, unlike the effects on skin.
2 citations
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January 2009 in “Journal of Drug Delivery Science and Technology” This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.
1 citations
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May 2022 in “Pharmaceutics” This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.
9 citations
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April 2019 in “International Journal of Molecular Sciences” This research indicates that KCED-1 and KCED-2 effectively induce adiponectin production in human subcutaneous fat, which may promote hair growth on the scalp.
1 citations
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October 2025 in “Beni-Suef University Journal of Basic and Applied Sciences” This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.
4 citations
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January 2018 in “Research journal of pharmacy and technology” This study found that Wera leaf extract, particularly its n-hexane fraction, significantly stimulated hair growth, suggesting its potential as an antialopecia treatment.
January 2017 in “Isan Journal of Pharmaceutical Sciences” This study explored microemulsion formulations for delivering finasteride through the skin, finding that higher water concentrations increased permeation, which may inform optimal transdermal delivery for treating androgenetic alopecia.
22 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
January 2006 in “Benzina: Revista d'excepcions culturals” This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.
This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.
20 citations
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February 2017 in “European journal of pharmaceutical sciences” This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.
4 citations
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July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” In this study, hirsute women treated with cyproterone acetate and ethinyloestradiol experienced significant reductions in sebum secretion and hair growth after several months.
43 citations
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July 2017 in “International journal of pharmaceutics” This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
117 citations
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November 2008 in “Drug Development and Industrial Pharmacy” This review discusses the use of microemulsions for transdermal drug delivery and emphasizes the importance of component selection for enhancing drug permeation and skin tolerance, without reporting new clinical results.
September 2025 in “Cosmetics” In this study, researchers found that the lipid composition in hair significantly affects water diffusion and may explain differences in dyeing and cosmetic treatment responses between Asian and European hair, with CP2 fibers having more lipids than CP3 fibers.
76 citations
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February 2015 in “Industrial Crops and Products” This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.
September 2020 in “Eureka: Health Sciences” In this study, the researchers developed an optimal emulgel formulation for treating androgenic alopecia, determining that a base with 0.3% Carbomer Ultraz 10, 0.1% potassium sorbate, and 0.2% triethanolamine offered the best properties for drug release, application compliance, safety, and stability.
4 citations
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March 2020 in “Cutaneous and ocular toxicology” In this double-blind, randomized controlled study, researchers found that Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner was similarly tolerated compared to three other hair cleansing conditioners and was significantly better tolerated than salicylic acid shampoo or baby shampoo in terms of skin reactions.
October 2025 in “Chinese Chemical Letters” Using a special solvent can make Cacumen Platycladi essential oil more effective for treating hair loss.
January 2026 in “International journal of research and scientific innovation” In this laboratory study, researchers developed a multifunctional organic hair cream with various natural extracts, finding that the cream with 15% extracts demonstrated higher physical stability, hair strength, and antimicrobial activity compared to lower concentration samples and synthetic alternatives.