The Effect of Dimethyl Sulfoxide on Percutaneous Absorption: A Mechanistic Study, Part III

January 1968

Stanley G. Elfbaum, Karl Laden

dimethyl sulfoxide DMSO percutaneous absorption hair fibers skin barrier lipid extraction protein swelling

From the encyclopedia

cosmetic product that temporarily makes hair appear thicker

Studysummary This study found that high concentrations of dimethyl sulfoxide are needed to cause significant swelling in hair fibers, though the swelling is reversible, unlike the effects on skin.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

View this study on journal.scconline.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Enhanced skin penetration of Finasteride loaded DMSO-liposomes for the treatment of androgenic alopecia: comparison with conventional liposomes

1 citations , January 2023 in “Drug Development and Industrial Pharmacy”

This study observed that DMSO-modified liposomes enhanced the topical delivery of finasteride, improving hair follicle density and growth phase ratio in a rat model of testosterone-induced alopecia.

research Enhancement of percutaneous absorption of Finasteride by cosolvents, cosurfactant and surfactants

24 citations , November 2009 in “Pharmaceutical Development and Technology”

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

research Hair removal and bioavailability of chemicals: Effect of physicochemical properties of drugs and surfactants on skin permeation ex vivo

10 citations , June 2019 in “International Journal of Pharmaceutics”

Hair removal methods damage the skin barrier and affect substance penetration.

research Evaluation of Human Hair Absorption and Retention

October 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study found that hair treated with a supplemental hair care product showed significantly higher absorption, deeper penetration, and reduced dryness compared to untreated and water-treated hair, as measured with 3D Raman spectroscopy.

research Dimethylsiloxane polymers for the effective transdermal delivery of Minoxidil in hair loss treatment

January 2025 in “Biomedical Engineering Letters”

This study reported that a new polymeric formulation for topical minoxidil delivery in an animal model improved hair growth and hair follicle formation more effectively than minoxidil in PBS, suggesting potential as a future hair loss treatment.