Influence of Hair Growth Cycle on Lipid Composition of Mouse Epidermis and Dermis
November 1960
in “
Experimental Biology and Medicine
”
TLDR Hair growth stages don't significantly change lipid content in mouse skin.
The study examined the water and lipid composition of mouse epidermis and dermis during the anagen VI (growing) and telogen (quiescent) stages of the hair growth cycle. Despite significant morphological differences in the corium and adipose layers during these stages, the total lipid, phospholipid, neutral lipid, cholesterol esters, cholesterol, and triglyceride content in both the epidermis and dermis did not show significant differences between the two stages. Regardless of hair growth activity, the epidermis consistently exhibited lower water content and higher levels of cholesterol, cholesterol esters, and phospholipids compared to the dermis, with fast-acting sterols in the epidermis primarily found in the esterified fraction.
