TLDR Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
The document discussed the use of microemulsions as a potential carrier for dermal drug delivery. Microemulsions were explored due to their ability to enhance the solubility and stability of drugs, improve drug absorption through the skin, and provide controlled release. The study highlighted the advantages of microemulsions, such as their thermodynamic stability, ease of preparation, and ability to incorporate both hydrophilic and lipophilic drugs. The research suggested that microemulsions could serve as an effective alternative to traditional carriers in dermal drug delivery systems, potentially improving therapeutic outcomes.
75 citations
,
August 2006 in “International Journal of Pharmaceutics” The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
61 citations
,
March 2006 in “Colloids and surfaces. B, Biointerfaces” Lecithin microemulsion safely delivers tetracaine hydrochloride through the skin.
32 citations
,
November 2004 in “Journal of pharmaceutical sciences” Different tea tree oil mixtures absorb into hair follicles at varying levels, with microemulsion being the most effective.
10 citations
,
February 2021 in “International Journal of Nanomedicine” Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
16 citations
,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
