Transdermal Drug Delivery of Finasteride Ethosomes and Finasteride Liposomes

    January 2007 in “ Zhōnghuá yàoxué zázhì ”
    Wenquan Liang
    TLDR Ethosomes deliver finasteride through the skin more effectively than liposomes.
    The study investigated the permeation characteristics of finasteride encapsulated in ethosomes and liposomes. Ethosomes, prepared by injection, were found to have a more condensed vesicular structure and higher encapsulation ability compared to liposomes, which were prepared by the film dispersing method. The transdermal flux of ethosomes was 1.34±0.11 μg·cm-2·h-1, which was 3.2 times higher than that of liposomes. Ethosomes also significantly increased the skin accumulation of finasteride, particularly in the deeper dermis layers, although the drug distribution ratio between the epidermis and dermis was reversed. The study concluded that the different percutaneous drug delivery characteristics of ethosomes and liposomes were crucial in selecting the appropriate carrier for the desired drug-release profile.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community How does low level laser therapy?

      in Chat  5 upvotes 10 months ago
      Low-level laser therapy (LLLT) is debated for hair regrowth, with some users suggesting it should be combined with treatments like minoxidil and finasteride for effectiveness. Many users express skepticism about LLLT's efficacy and cost, emphasizing the need for the correct wavelength and quality devices.

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 10 months ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  19 upvotes 2 weeks ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

      community find a cure for this shit already

      in Chat  208 upvotes 5 years ago
      Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

    Related Research

    1 / 1 results