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research Influence of Liposome Type and Skin Model on Skin Permeation and Accumulation Properties of Genistein

12 citations , July 2010 in “Journal of Dispersion Science and Technology”

This study found that elastic liposomes enhanced skin delivery of genistein in haired skin compared to conventional liposomes, but showed decreased effectiveness in hairless skin.

research 253 Protective and cleansing effect of a skin care product against pollen allergen accumulation in the hair follicle

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that a skincare product effectively prevented and reduced pollen allergen accumulation in hair follicle models by forming a protective film and exhibiting strong cleansing properties, suggesting its potential to protect skin from environmental elements that can lead to irritation and allergic reactions.

research Accumulation of I131 by the skin and hair of animals and man

December 1963 in “Bulletin of Experimental Biology and Medicine”

Radioiodine-131 significantly accumulates in skin and hair.

research Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin

44 citations , April 2003 in “European journal of pharmaceutical sciences”

This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.

research In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers

84 citations , July 2008 in “Aaps Pharmscitech”

Ethosomes improve finasteride delivery through skin for hair loss treatment.

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Community Join

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community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 1 year ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

community 6 Month Progress. Dutasteride Saved My Hair.

in Progress Pictures 185 upvotes 9 months ago

The user experienced significant hair regrowth and acne reduction after six months of using 0.5 mg dutasteride and 2.5 mg oral minoxidil daily. Despite initial shedding, the user's hair became thicker and darker, with no side effects other than improved skin.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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Experts

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SMP Specialist
Noelle Skin
Nice, France

Noelle Skin