In Vivo Hair Re-Growth Efficacies of Minoxidil Preparations: Distearyldimethylammonium Chloride Vesicles, Cellulose Acetate Phthalate Microparticles, and Poloxamer Solution

    January 2009 in “ Journal of Drug Delivery Science and Technology ”
    Jung-Hyun Kim
    Image of study
    TLDR Minoxidil in distearyldimethylammonium chloride vesicles significantly promotes hair growth, while minoxidil in microparticles or poloxamer solutions doesn't.
    In a 2008 study, three minoxidil (MXD) preparations were tested for their hair re-growth efficacy: distearyldimethylammonium chloride (DSDMAC) vesicles, cellulose acetate phthalate microparticles, and poloxamer solution. The study found that MXD encapsulated in DSDMAC vesicles significantly promoted hair growth due to their small size, flexibility, and positive surface charge, which allowed for increased skin permeation and retention. In contrast, MXD in microparticles or poloxamer solutions did not show significant hair growth promotion.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community Scared of Twink death due to minoxidil

      in Minoxidil 1 week ago
      A 19-year-old is considering switching from topical to oral minoxidil to combat hair loss, despite concerns about increased body hair. They are currently using minoxidil, ketoconazole shampoo, and dutasteride, and are willing to accept the trade-off of more body hair for better scalp hair growth.

      community Foam minoxidil with Tretinoin (Which Tretinoin Strength?)

      in Minoxidil  2 upvotes 1 week ago
      The conversation discusses using foam minoxidil with tretinoin cream for hair loss, with users sharing experiences on tretinoin strengths of 0.025% and 0.05%. Some users report irritation with higher tretinoin concentrations and note that foam minoxidil may be less effective than liquid.

      community 3,5 months of only topical minoxidil

      in Minoxidil  762 upvotes 1 week ago
      A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.

    Similar Research

    5 / 1000+ results