268 citations
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April 2009 in “International Journal of Pharmaceutics” In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.
August 2018 in “Journal of the American Academy of Dermatology” A new cosmetic cream reduced facial redness and skin temperature after 4 weeks of use.
February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
20 citations
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June 2014 in “Pharmaceutical research” This study found that combining Aliaxin® Global Performance with Viscoderm® Skinkò E improved hydration and appearance of nasolabial folds more effectively than using Aliaxin® Global Performance alone.
41 citations
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May 2018 in “Nutrition and healthy aging” This study suggests that age-related changes in skin elasticity reduce its stability against wrinkling, and anti-aging strategies should focus on addressing elastic mismatches between skin layers.
July 2007 in “International Journal of Cosmetic Science” This study found that a new hybrid polymer made from hydrolyzed protein, alkyl chain, and silicone helped prevent discoloration and improve moisture feel and manageability in dyed and damaged hair.
13 citations
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January 2015 in “Molecular Pharmaceutics” This study suggests that minoxidil may serve as a suitable reference drug for high permeability classification in the Biopharmaceutics Classification System due to its consistent permeability across different intestinal segments and pH levels.
1 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” This study found that low-molecular-weight hyaluronate significantly improved the mechanical strength and elastic modulus of overbleached hair by enhancing hydrogen bond networks within keratin.
November 2025 in “Journal of Pharmacognosy and Phytochemistry” This study aimed to formulate and test a hair conditioning mask using natural ingredients like flax seeds, rice water, and vitamin E, suggesting potential benefits in addressing issues like hair loss, dryness, frizziness, dullness, and dandruff while meeting customer demand for strong and shiny hair.
3 citations
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September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
December 2025 in “Applied Sciences” This study examined argan oil inclusion complexes with β-CD, finding that these complexes improve the antibacterial efficacy, uniformity, and mechanical performance of hair treatment formulations while enhancing the durability of bleached hair, suggesting their potential as stable and effective cosmetic ingredients.
September 2023 in “Journal of the American Academy of Dermatology” In this study, a cleanser gel with salicylic acid, vitamin C, and Lens esculenta seed extract reduced facial oiliness by 44.9% after 2 hours and by 19.1% after 4 hours in subjects with oily skin, using a novel facial oiliness mapping method.
This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.
17 citations
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October 2003 in “Contact dermatitis” Glycerin in hand cream can cause allergic skin reactions.
July 2026 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, hair tonic formulations containing moringa leaf extract and honey were tested for stability and found to remain stable and non-irritating after storage, meeting specific quality standards.
This study developed a novel protocol that demonstrated improved localized delivery of minoxidil to eyebrow application sites with minimal runoff, compared to a control formulation.
2 citations
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January 2008 in “Journal of Society of Cosmetic Chemists of Japan” PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.
July 2023 in “International journal of advanced research in medical and pharmaceutical sciences” In this study, researchers formulated and evaluated a gel containing minoxidil and aloe vera for alopecia treatment, finding that it was stable and non-irritant on albino rats, suggesting enhanced topical drug delivery over traditional solutions.
19 citations
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October 1989 in “PubMed” This study found that sulfation of minoxidil occurs in hair follicles and proliferative keratinocytes, which may be linked to its hair growth stimulation effects.
11 citations
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December 2011 in “International journal of pharmaceutics” In this study, brief ultrasound exposure reduced the follicular contribution to hydrocortisone absorption while significantly increasing total skin permeability, likely due to removal of the upper stratum corneum.
7 citations
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April 2018 in “Cosmetics” This study found that the medulla of Japanese hair contains unsaturated lipids such as squalene and oleic acid, which may contribute to hair glossiness.
24 citations
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January 2003 in “Drug Delivery” This study found that only minoxidil encapsulated in cationic vesicles significantly promoted hair growth in mice, likely due to its higher retention on the skin.
9 citations
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July 2017 in “Journal of Drug Delivery Science and Technology” This study suggests that a microemulsion formulation of Minoxidil effectively enhances drug delivery through hair follicles, showing significant follicular response alterations in an alopecia model.
4 citations
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June 2023 in “Pharmaceutical Biology” This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that a novel bioengineered microneedle patch successfully delivered minoxidil to induce hair growth in a mouse model, suggesting a promising approach to improve treatment for androgenetic alopecia.
July 2026 in “International Journal of Biology Pharmacy and Allied Sciences” This study highlights the potential benefits of combining dermoscopy with natural oil blends to improve the treatment of skin disorders and enhance patient compliance, but it emphasizes the need for further large-scale research to optimize these approaches in dermatology.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a multipurpose herbal gel formulation containing ingredients like lotus, aloe, and turmeric, which was reported to improve hair manageability and skin care while being non-irritant and cost-effective.
28 citations
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September 2023 in “International Journal of Biological Macromolecules” Animal experiments in this study demonstrated that a new sandwich-like fiber/sponge dressing design, which enhances wound healing through improved moisture management and faster exudate evaporation, resulted in more significant wound size reduction compared to commercial and control dressings.
4 citations
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February 2015 in “PubMed” This study found that a minoxidil foamable emu oil emulsion significantly promoted hair growth in animals compared to a marketed 5% minoxidil solution, showing increased hair follicles in the anagenic phase.