Improving The Mechanical Properties Of Damaged Hair Using Low-Molecular Weight Hyaluronate

November 2022 in “ Molecules/Molecules online/Molecules annual ”

Wenjie Qu, Xiaokui Guo, Guixin Xu, Songyan Zou, Yue Wu, Chen-Yu Hu, Kuan Chang, Jing Wang

low-molecular weight hyaluronate hyaluronate hair cortex keratin hydrogen bonds tensile strength elastic modulus hair damage repair low-MW HA HA

TLDR Low-molecular weight hyaluronate can make damaged hair stronger.

The study found that low-molecular weight hyaluronate (low-MW HA) significantly improved the mechanical properties of over-bleached hair by enhancing tensile strength and elastic modulus by nearly 16%. Low-MW HA penetrated deep into the hair cortex, forming additional intermolecular hydrogen bonds within hair keratin, and improved water bonding, which contributed to the enhanced mechanical properties. This highlights the potential of low-MW HA in hair damage repair and its application in hair care products.

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Improving The Mechanical Properties Of Damaged Hair Using Low-Molecular Weight Hyaluronate

Research cited in this study

research Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model

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research Insights on the Mechanical Behavior of Keratin Fibrils

research Protein Disulfide Isomerase-Mediated Grafting of Cysteine-Containing Peptides onto Over-Bleached Hair

research Significant Damage of the Skin and Hair Following Hair Bleaching

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