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This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.

This study demonstrated that hyaluronan gel is a promising biomaterial for 3-D in vitro culture of mouse ovarian follicles, supporting the production of fertilizable metaphase II oocytes.

This study reported that a newly developed bioadhesive and injectable hydrogel dressing, incorporating hyaluronate-gelatin and the antibiotic doxycycline, accelerated burn wound healing and skin regeneration in rats, highlighting its potential for clinical applications in burn injury therapy.

This study found that cutaneous myxomas showed decreased CD44 expression in follicular epithelial proliferations, which may be related to abnormal hyaluronate accumulation in these lesions.

This study found that low-molecular-weight hyaluronate significantly improved the mechanical strength and elastic modulus of overbleached hair by enhancing hydrogen bond networks within keratin.