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Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Cannabinoids may help treat various skin conditions.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Mutations in the RBPJ gene cause Adams-Oliver Syndrome.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Hairless protein can block vitamin D activation in skin cells.

TRPV3 in skin cells causes inflammation and cell death.

FGF5 gene mutations cause long hair in domestic cats.

Trichoscopy is a quick and easy way to diagnose most genetic hair problems without invasive methods.

Hair follicles in mutant mice self-organize into ordered patterns within a week.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Cetaceans lost hair due to changes in the Hr and FGF5 genes.

Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.

Significant progress was made in understanding PXE, but effective treatments are still needed.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

Hidradenitis suppurativa might be a type of autoinflammatory skin disease.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Notch signaling disruptions can cause various skin diseases.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.