Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease

    May 2020 in “ Frontiers in immunology ”
    Toshifumi Nomura
    Studysummary This review discusses the genetic, autoinflammatory, and keratinization factors involved in hidradenitis suppurativa and presents the concept of classifying it as an autoinflammatory keratinization disease, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 4

    1. Hidradenitis Suppurativa and Mediterranean Fever Gene Mutations JAAD Case Reports · 2019
    2. Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages Human Molecular Genetics · 2018
    3. T Helper 17 Cell/Regulatory T-Cell Imbalance in Hidradenitis Suppurativa/Acne Inversa: The Link to Hair Follicle Dissection, Obesity, Smoking, and Autoimmune Comorbidities British journal of dermatology/British journal of dermatology, Supplement · 2018
    4. Mutations in Gamma-Secretase Subunit-Encoding PSENEN Underlie Dowling-Degos Disease Associated with Acne Inversa Journal of Clinical Investigation · 2017