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    Glossary Interleukin-36

    group of cytokines involved in immune system signaling and inflammation

    Interleukin-36 (IL-36) is a group of cytokines, which are small proteins important for cell signaling in the immune system. These cytokines play a crucial role in inflammatory responses and are involved in the pathogenesis of various autoimmune and inflammatory diseases, such as psoriasis. IL-36 includes three agonists (IL-36α, IL-36β, and IL-36γ) and an antagonist (IL-36Ra), which together help regulate the body's immune response.

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    1. Interleukin-36 role in the severity of acne vulgaris: A case control study Research Square · 2026
    2. IL-36α Promoted Wound Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation Frontiers in Cell and Developmental Biology · 2020 · 7 citations
    3. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    4. Topical olive oil with downregulation of stress factors protects mice skin from precarious 3600 MHz electromagnetic radiation. The Egyptian Journal of Histology · 2020
    5. Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease Frontiers in immunology · 2020 · 41 citations
    6. Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils 2020 · 16 citations
    7. Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue Clinical Science · 2019 · 8 citations
    8. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    9. Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells JEADV Clinical Practice · 2023 · 3 citations
    10. Increased serum interleukin-17A levels correlate with disease severity and poor prognostic factors in patients with alopecia areata Dermatology Reports · 2021
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