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This study developed a multifunctional bilayer dressing containing nanosilver and basic fibroblast growth factor, which improved wound healing by preventing bacterial penetration, promoting angiogenesis and hemostasis, and accelerating cell proliferation and migration, outperforming a control group by increasing healing rates by 47% in vivo.

This study found that cold atmospheric plasma can accelerate wound healing processes and reduce bacterial growth, including drug-resistant strains, suggesting its potential as a novel treatment for chronic wounds.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

This review suggests that induced pluripotent stem cells (iPSCs) hold promise for treating chronic wounds, but further work is needed to address safety, efficacy, and translation from preclinical models to real-world applications.

This study found that a catechins-rich Assam tea extract demonstrated antioxidant effects and hair growth promotion in mice, suggesting its potential as a natural alternative for treating hair loss.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

This study suggests that sweat glands may have an immune privilege similar to hair follicles, and disruptions in this could contribute to autoimmune skin diseases.

This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.

This study found that after injury, the bone marrow microenvironment's increased Wnt10b expression supports hematopoietic stem cell regeneration by enhancing Wnt signaling, revealing a vital interaction during recovery.

This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.

This study found that angiogenin is expressed in human dermal papilla cells, where it might stimulate hair growth by promoting cell proliferation and local skin angiogenesis.

This study established a novel in vivo "whisker follicle microinjection assay" using mouse whiskers to evaluate hair growth and pigmentation effects of various chemicals and proteins, identifying minoxidil, ruxolitinib, and RSPO1 as growth promoters, while deoxyarbutin inhibited pigmentation and Nbl1 emerged as a growth inhibitor.

This study found that elevated STAT5 levels are linked to improved hair-inducing capabilities in human dermal papilla cells, and reducing STAT5 impairs hair follicle induction.

This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This study found that Caspase-1, traditionally viewed as an inflammasome component, is secreted upon wounding and plays a novel role by triggering hair follicle stem cell migration into the epidermis, offering insights into epithelial hyperplasia mechanisms in inflammatory skin conditions.

This study demonstrates that SDF-1/CXCL12 and CXCR4 signaling play a crucial role in directing the migration and positioning of melanoblasts in mouse hair follicle formation.

This study found that allergen treatment in alopecia areata mice appeared to alter leukocyte subset distribution and impaired dendritic cell migration, which may affect T-cell activation and hair follicle recovery.

This study found that EGCG, a compound from green tea, may enhance the proliferation and antioxidant activity of dermal papilla cells by upregulating VEGFA expression, potentially aiding hair follicle growth.

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

In this study, researchers demonstrated that their technology efficiently produces CFx-δ2 from stem cells and accelerates wound healing by enhancing fibroblast activity, reducing inflammation, and promoting blood vessel formation.

This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.

This study found that activin B promotes epithelial wound healing in mice through the RhoA-Rock-JNK-cJun signaling pathway, suggesting a potential therapeutic role for activin B in wound repair.

This study found that ALKBH5 plays a critical role in wound re-epithelialization by enhancing the stability of PELI2 mRNA, and its absence delays wound healing. Supplementation with PELI2 can partially rescue this delay, pointing to potential new therapies for stubborn wounds.

In this study, exosome-like nanoparticles derived from rose stem cell culture were found to enhance skin quality by increasing collagen production, reducing melanin and inflammation, and promoting cell migration in vitro, suggesting potential aesthetic applications.

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

This study found that human progenitor keratinocytes form unique complements of enhancers and super-enhancers during differentiation and migration, influencing gene expression and skin disease variant enrichment.