Catechins-Rich Tea Extract and Its Functional Properties Mitigating Hair Loss

November 2025 in “ Discover Food ”

Mayuree Kanlayavattanakul, Garry Ka-Wing Yuen, Piyaporn Chueamchaitrakun

catechins-rich tea extract Assam tea androgenic alopecia EGCG valproic acid antioxidant activity cellular proliferation inflammation human follicle dermal papilla cells hair shafts green tea extract epigallocatechin gallate valproate

Studysummary This study found that a catechins-rich Assam tea extract demonstrated antioxidant effects and hair growth promotion in mice, suggesting its potential as a natural alternative for treating hair loss.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

15 / 15 results

Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia

research Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia

May 2025 in “Journal of Inflammation Research”

This study found that NK and CD8+ T cell infiltration may drive inflammation in androgenetic alopecia, suggesting that targeting IL-15 signaling could offer a new therapeutic approach for hair regeneration.

research Epigallocatechin-3-Gallate Promotes Dermal Papilla Cell Proliferation and Migration Through VEGFA Induction

January 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research”

This study found that EGCG, a compound from green tea, may enhance the proliferation and antioxidant activity of dermal papilla cells by upregulating VEGFA expression, potentially aiding hair follicle growth.

research Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants

41 citations , June 2024 in “Journal of Cellular and Molecular Medicine”

This study reviews how oxidative stress affects hair follicle development and hair growth, discusses antioxidant-based treatments for hair loss, and evaluates natural antioxidant products that promote hair growth, emphasizing the need for further research due to existing limitations.

research Interleukin-15 Is a Hair Follicle Immune Privilege Guardian

1 citations , April 2024 in “Journal of Autoimmunity”

This study found that rhIL-15 promotes human hair follicle growth and regrowth in experimental settings and may have therapeutic potential for alopecia areata by restoring immune privilege guardianship.

research The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model

May 2023 in “Scientific Reports”

This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.

research Vitamins and Their Derivatives Synergistically Promote Hair Shaft Elongation via PlGF/VEGFR-1 Signalling Activation

1 citations , September 2022 in “Journal of dermatological science”

This study found that a combination of vitamins in hair care products promoted hair shaft elongation in a mouse model by activating the PlGF/VEGFR-1 signaling pathway.

research Evaluation of Hair Growth Properties of Topical Kombucha Tea Extracts

8 citations , January 2021 in “Advances in Traditional Medicine”

In this study, black tea kombucha with and without MSM significantly improved hair density and length in mice, suggesting its potential as a natural hair regrowth treatment.

research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods

28 citations , March 2019 in “Journal of Dermatological Science”

This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , December 2018 in “Journal of autoimmunity”

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.

research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth

76 citations , August 2018 in “International Journal of Cosmetic Science”

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

research Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment

47 citations , August 2016 in “Fitoterapia”

This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.

research Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells

16 citations , January 2016 in “Annals of Dermatology”

This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.

research Green Tea in Dermatology: Myths and Facts

20 citations , July 2015 in “Journal der Deutschen Dermatologischen Gesellschaft”

This review summarizes the anticarcinogenic, anti-inflammatory, and other health effects of green tea, noting its historical and ongoing use in dermatological and cosmeceutical applications, but reports no new clinical results.

research Hair Loss and Herbs for Treatment

39 citations , September 2013 in “Journal of Cosmetic Dermatology”

This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.

research Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG)

108 citations , November 2006 in “Phytomedicine”

This study found that EGCG from green tea may stimulate human hair growth by promoting the proliferation and anti-apoptotic activity in dermal papilla cells.