Effect of Scenedesmus Deserticola JD052 Extracts on Hair Inductivity by Regulating the AKT and GSK3β/β-Catenin Signaling Pathways in Human Dermal Papilla Cells
February 2025
in “
Applied Sciences
”
Scenedesmus deserticola JD052 human dermal papilla cells AKT signaling pathway GSK3β/β-Catenin signaling pathway photoautotrophic extracts heterotrophic extracts β-catenin dermal papilla signature genes keratinocyte migration VEGF IGF-1 pheophorbide A linolelaidic acid HDP cells vascular endothelial growth factor insulin-like growth factor 1
Studysummary This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.
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