Novel, Reproducible Consortia Factors Derived from Adipose Stem Cells for Burn Wound Treatment

June 2025 in “ Stem Cells and Cloning Advances and Applications ”

Dodanim Talavera‐Adame, Melissa Palomares, Mikhail Plaza, Nualla Rogowski, Bong Seop Lee, Assaf Zemach, Nathan Newman

adipose stem cells fibroblast proliferation angiogenesis inflammation

Studysummary In this study, researchers demonstrated that their technology efficiently produces CFx-δ2 from stem cells and accelerates wound healing by enhancing fibroblast activity, reducing inflammation, and promoting blood vessel formation.

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The study presents a technology that efficiently derives and scales up CFx-δ2 from immortalized adipose stem cells, which is effective in treating burn wounds. The product enhances wound healing by boosting fibroblast proliferation and migration, reducing inflammation, and promoting angiogenesis.

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Research cited in this study

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research Wound Healing: A Cellular Perspective

1160 citations , November 2018 in “Physiological Reviews”

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

research Conventional and Novel Stem Cell-Based Therapies for Androgenic Alopecia

22 citations , August 2017 in “Stem cells and cloning”

This review analyzes therapies used for androgenic alopecia, highlighting potential advances from stem cell technologies and regenerative medicine, and reports no new clinical results.