Impairment of Hair-Inducing Capacity of 3D-Cultured Human Dermal Papilla Cells by the Ablation of STAT5

April 2018 in “ Journal of Investigative Dermatology ”

Changhoon Seo, Mi Hee Kwack, M. Kim … Young Kwan Sung

STAT5 dermal papilla cells small interfering RNA 3D-cultured DP spheres patch hair reconstitution assay trichogenic DP spheroids hair follicle induction newborn mouse epidermal cells siRNA DP cells 3D DP spheres hair reconstitution trichogenic DP spheres hair follicle formation

Studysummary This study found that elevated STAT5 levels are linked to improved hair-inducing capabilities in human dermal papilla cells, and reducing STAT5 impairs hair follicle induction.

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