Search

for
Search:

Did you mean Lymphocytic Infiltration?

GlossaryLymphocytic Infiltration

accumulation of immune cells in tissue causing inflammation

Lymphocytic infiltration refers to the accumulation of lymphocytes, a type of white blood cell, in a particular tissue or organ. This often occurs as part of the body's immune response to infection, inflammation, or autoimmune conditions, where the immune system mistakenly attacks healthy cells. In the context of hair and alopecia, lymphocytic infiltration can be seen in conditions like alopecia areata, where the immune system targets hair follicles, leading to hair loss.

Related Terms

Sort by

Research

30 / 1000+ results

Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases

research Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases

September 2017 in “Journal of Investigative Dermatology”

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Immune Response Involving the Bulge Region in Addition to Telogen Conversion Contributes to Hair Loss in a Case of Atypical Drug-Induced Hypersensitivity Syndrome

research Immune Response Involving the Bulge Region in Addition to Telogen Conversion Contributes to Hair Loss in a Case of Atypical Drug-Induced Hypersensitivity Syndrome

1 citations, October 2013 in “The Journal of Dermatology”

Hair loss in a drug reaction case involved both a common shedding phase and an immune attack on hair follicle stem cells.

research Phenobarbital

January 2014 in “Reactions Weekly”

A woman experienced unusual hair loss and skin reactions after taking phenobarbital, but her hair grew back after treatment.

Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

research Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

20 citations, December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

research Use of Trichoscopy for the Diagnosis of Alopecia Areata Coexisting with Primary Scarring Alopecia in a Female Hair Loss Patient

2 citations, March 2019 in “Journal of Dermatology”

Trichoscopy helped diagnose and treat a woman with two different types of hair loss.

research Unilateral Widespread Lichen Planus Following Blaschko's Lines After Mycoplasma Pneumoniae Infection

1 citations, September 2013 in “The Journal of Dermatology”

An 8-year-old girl developed a rare skin condition in a linear pattern on one side of her body after a lung infection, which improved with treatment.

research Establishment and Characterization of Human Sebocytic Progenitor Cells That Can Differentiate Into Functional Sebocytes

September 2017 in “Journal of Investigative Dermatology”

Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.

research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells

1 citations, September 2017 in “Journal of Investigative Dermatology”

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

research Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases

May 2023 in “Journal of Clinical Medicine”

New understanding and treatments for hair loss are improving, but more research is needed.

research Clinical And Histological Recovery Of Non-Thymoma-Associated Exfoliative Dermatitis In A Cat Treated With Ciclosporin A

1 citations, January 2020 in “Journal of Feline Medicine and Surgery Open Reports”

Ciclosporin A effectively treated a cat's severe skin condition.

research Expression Patterns of the Siah Genes in Postnatal Mouse Skin

September 2017 in “Journal of Investigative Dermatology”

The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.

Tissue and Circulating MicroRNA Co-Expression Analysis Reveals Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia

research Tissue and Circulating MicroRNA Co-Expression Analysis Reveals Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia

September 2017 in “Journal of Investigative Dermatology”

Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.

research Is EBF1 a Negative Regulator of WNT10A in the Development of Androgenetic Alopecia?

September 2017 in “Journal of Investigative Dermatology”

Finasteride helps female-pattern hair loss.

research Roles of Tumor Suppressors in Regulating Tumor-Associated Inflammation

44 citations, September 2014 in “Cell Death & Differentiation”

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

research Skin

2 citations, January 2011 in “Elsevier eBooks”

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models

24 citations, January 2008 in “KARGER eBooks”

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

research Case Report: Sequential Therapy with Dupilumab and Baricitinib for Severe Alopecia Areata with Atopic Dermatitis in Children

June 2024 in “Frontiers in immunology”

Sequential therapy with dupilumab and baricitinib improved hair regrowth and atopic dermatitis in a child without adverse reactions.

research Human αβ and γδ T Cells in Skin Immunity and Disease

83 citations, June 2018 in “Frontiers in immunology”

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Flightless I Exacerbation of Inflammatory Responses Contributes to Increased Colonic Damage in a Mouse Model of Dextran Sulfate Sodium-Induced Ulcerative Colitis

research Flightless I Exacerbation of Inflammatory Responses Contributes to Increased Colonic Damage in a Mouse Model of Dextran Sulfate Sodium-Induced Ulcerative Colitis

13 citations, September 2019 in “Scientific Reports”

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas

68 citations, September 2003 in “British Journal of Dermatology”

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

research Dermatitis Cruris Pustulosa Et Atrophicans: Scarring Alopecia Beyond Scalp Hair

1 citations, January 2022 in “Skin appendage disorders”

DCPA is a chronic skin condition affecting the legs, often misdiagnosed, and needs more research for better understanding and treatment.

research Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum

22 citations, June 2013 in “Australasian Journal of Dermatology”

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

research Case of Alopecia Induced by Sorafenib, Possible Mechanism Similar to Alopecia Areata

4 citations, November 2017 in “The Journal of Dermatology”

Sorafenib may cause hair loss in a way similar to alopecia areata.

research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research CD80CD86 Deficiency Disrupts Regulatory CD4+FoxP3+ T Cell Homeostasis and Induces Autoimmune-Like Alopecia

6 citations, April 2017 in “Experimental dermatology”

CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.

research Central Centrifugal Cicatricial Alopecia Gene Expression Analysis Revealed Cholesterol, Fatty Acid, and Mast Cell Pathways

April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.

research Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study

December 2020 in “Galen Medical Journal”

Alopecia patients have more mast cells in their scalps, especially in severe cases and older age, with alopecia areata showing the highest increase.

Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study

research Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study

December 2020 in “Galen Medical Journal”

People with Alopecia Areata and Androgenic Alopecia have more mast cells in their scalp than healthy individuals, especially those with Alopecia Areata.

research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice

August 2016 in “Journal of Dermatology”

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

research Localized Telogen Effluvium Following Hair Transplantation

May 2015 in “Journal of The American Academy of Dermatology”

Some people may temporarily lose more hair in certain areas after a hair transplant.