Case Report: Sequential Therapy with Dupilumab and Baricitinib for Severe Alopecia Areata with Atopic Dermatitis in Children

    June 2024 in “ Frontiers in immunology ”
    Huijuan Fang, Zhang Feng-chuan, Weiren Lin … Dingquan Yang
    Studysummary In this case report, an 8-year-old with severe alopecia areata and atopic dermatitis experienced significant hair regrowth and improved dermatitis symptoms after treatment with dupilumab followed by baricitinib, with no major side effects observed.
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    Research cited in this study 13

    1. Baricitinib for the Treatment of Alopecia Areata Drugs · 2023
    2. Dupilumab in Inflammatory Skin Diseases: A Systematic Review Biomolecules · 2023
    3. Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population JAMA Dermatology · 2023
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    5. Alopecia Areata and Risk of Atopic and Autoimmune Conditions: Population-Based Cohort Study Clinical and Experimental Dermatology · 2022
    6. An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata Frontiers in immunology · 2022
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    9. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
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    11. Alopecia Areata in Severe Atopic Dermatitis Treated With Dupilumab Journal of Investigational Allergology and Clinical Immunology · 2018
    12. Alopecia Areata After Dupilumab for Atopic Dermatitis JAAD case reports · 2018
    13. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017