Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.

This study suggests that dermal adipocytes play a significant role in skin aging, particularly through the process of adipocyte-myofibroblast transition, highlighting them as potential targets to combat aging in chronically photo-damaged skin.

According to this study, individuals with Systemic Lupus Erythematosus in Mauritius face significant emotional, social, and practical challenges, and the researchers emphasize the need for better public education, employer sensitivity, and support groups to improve patients' quality of life.

In this study, LC-OCT imaging was found to noninvasively identify specific features of cicatricial alopecia due to lupus erythematosus, such as hyperreflective collagen fibers, which may aid in distinguishing it from other types of scarring alopecia.

This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.

This case report illustrates that prompt diagnosis and treatment of myositis in an SLE patient can lead to symptom resolution and highlights this condition as a rare SLE complication.

This study suggests that Arabs with systemic lupus erythematosus in Dubai show similar clinical features to patients from other Arab and Western countries, with a notable prevalence of positive anti-Ro antibodies.

This study reports two cases of follicular lichen planus, suggesting that GLPLS and LPP may be variants of this condition based on clinical and immunofluorescent findings.

This study found that chemical lumbar sympathectomy with 5% phenol effectively treated idiopathic livedo reticularis in most patients, offering a potential long-lasting solution with repeatable efficacy upon recurrence.

Tumescent local anesthesia is a safe, cost-effective method for outpatient liposuction.

This case report details two patients with Graham-Little-Piccardi-Lassueur syndrome who showed marked skin lesion improvement with corticosteroid treatment, though cicatricial scalp alopecia remained unresponsive.

In this case report, the patient was diagnosed with oral lichen sclerosus following a detailed clinical and histological examination and referral to dermatology, and it underscores the importance of interdisciplinary collaboration in managing this rare condition and its associated risks.

This study reports a novel LSS gene mutation in an Egyptian family with alopecia intellectual disability syndrome 4, expanding the known clinical and genetic features of the condition.

This report documents a case of Cronkhite-Canada Syndrome in a 56-year-old Laotian man, who successfully improved with vitamin supplementation and medical treatment after experiencing weight loss, alopecia, and gastrointestinal polyposis.

This study found that among 26 pregnant patients with Systemic Lupus Erythematosus, the most common pregnancy complication was intrauterine growth restriction.

This case report describes a rare instance of a Leydig cell tumor in a 35-year-old pregnant woman, discovered incidentally during a cesarean section. The tumor typically presents with symptoms of excess androgen, though it can range from asymptomatic to rapid virilization.

S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.

This study concluded that removing alopecia and mucous membrane components from the CLASI-A score limits the ability to capture crucial clinical information about cutaneous lupus erythematosus activity, recommending their retention.

This case report presents the first documented instance of basal cell carcinoma and cutaneous leiomyosarcoma occurring as a collision neoplasm in the same biopsy specimen.

In this study, researchers found that systemic lupus erythematosus significantly affects the self-image of many men, impacting their sense of masculinity and self-worth due to physical and psychosocial challenges, while a minority felt no effect.

This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.

In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.

This study engineered a bioluminescent yeast strain responsive to androgenic chemicals, demonstrating rapid and sensitive detection suitable for high-throughput screening and environmental monitoring.

This study identified a novel splice site mutation in the LIPH gene associated with autosomal recessive woolly hair, contributing to understanding the genetic basis of this condition.

A man with both skin lesions and lung cancer improved quickly with chemotherapy, suggesting the skin condition might be a reaction to immune system injury.

This case report describes a 14-year-old girl with Loose Anagen Hair Syndrome successfully treated with a combination of oral Minoxidil and Silicon supplements.

This study found two patterns of Type 2 SLE symptoms: Intermittent symptoms resolving with Type 1 symptom remission and Persistent symptoms continuing regardless of Type 1 symptom activity.

This study concluded that label-retaining cells in mouse epidermis differ in their sensitivity to proliferative stimuli, influencing their division and potential transdifferentiation without consistently depleting their population.

This case report identified cutaneous epitheliotropic T-cell lymphoma in a 3-year-old male sugar glider after skin biopsies, highlighting the need for thorough diagnostic evaluations in exotic pets.