Systemic Treatment with a KLK5 Inhibitor Shows Efficacy in a Murine Model of Netherton Syndrome

    Hiroyuki Takahashi, Hajime Yano, D. Nishimiya … T. Nishizawa
    Studysummary This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.
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