Pure Leydig Cell Tumor of the Ovary: A Rare Presentation of a Rare Entity in a Pregnant Patient

    November 2024 in “ Future Science OA
    Anwar Rjoop, Alia Al-Mohtaseb, Daoud O Al Aruri, Dina Hyari, Mohammad Abu Shugaer
    Studysummary This case report describes a rare instance of a Leydig cell tumor in a 35-year-old pregnant woman, discovered incidentally during a cesarean section. The tumor typically presents with symptoms of excess androgen, though it can range from asymptomatic to rapid virilization.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This case study discusses a rare instance of a pure Leydig cell tumor (LCT) in a 35-year-old pregnant woman, discovered incidentally during a cesarean section. LCTs are uncommon ovarian tumors, representing less than 0.1% of all ovarian tumors, and are typically associated with androgen excess. However, this patient was asymptomatic, likely due to pregnancy masking symptoms. The 9 cm tumor was benign, confirmed through histopathological examination, and required no further treatment post-surgery. Both the mother and baby were healthy nine months later. This case underscores the importance of considering LCT in differential diagnoses of hyperandrogenism, even in asymptomatic pregnant patients.
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