Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports and Review of the Literature

    L. Dourmishev, N. Mironova, I. V. Popov, Dina S. Rusinova, Maria Balabanova, Ljubka Miteva
    TLDR The document concludes that treatment improved skin lesions but not scalp hair loss in two patients with Graham-Little-Piccardi-Lassueur syndrome.
    Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare condition marked by cicatricial alopecia of the scalp, non-cicatricial alopecia of the axilla and groin, and follicular lichen planus eruptions. Two cases were reported: a 71-year-old woman and a 48-year-old man, both presenting with pruritic skin lesions and hair loss. Laboratory tests were normal, and histological examinations confirmed GLPLS. Treatment with systemic and local corticosteroids led to significant improvement in skin lesions, but cicatricial scalp alopecia did not respond to the treatment.
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