Cicatricial (Scarring) Alopecia: Clinical Presentations, Etiologies, and Histopathologic Features

    Virendra Sehgal, Govind Srivastva, Pramila Bajaj
    Image of study
    TLDR Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
    The 2001 document reviews cicatricial (scarring) alopecia, detailing the clinical presentations, potential etiologies, and histopathologic features of various forms such as lichen planopilaris, pseudopelade, discoid lupus erythematosus, folliculitis decalvans, and others. It highlights the importance of histopathology and immunofluorescence in diagnosis, noting the difficulty in differentiating between early lesions of these conditions. The review suggests that different scarring alopecias may represent stages of a single disease process, emphasizing the need for accurate diagnosis through detailed history, laboratory data, and advanced techniques to prevent permanent hair follicle damage.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 13 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 6 months ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

    Related Research

    2 / 2 results