Vertical and Transverse Sections of Alopecia Biopsy Specimens: Combining the Two to Maximize Diagnostic Yield

March 1995 in “ Journal of The American Academy of Dermatology ”

Dirk M. Elston, Martha L. McCollough, Vincent L. Angeloni

alopecia biopsy vertical sections transverse sections hematoxylin-eosin staining direct immunofluorescence lupus erythematosus lichen planopilaris follicular degeneration syndrome interface changes lupus panniculitis miniaturized hairs trichomalacia H-E staining immunofluorescence

Studysummary This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on jaad.org →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.

research The Transverse Anatomy of Androgenic Alopecia

42 citations , December 1990 in “The Journal of Dermatologic Surgery and Oncology”

This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.

research Alopecia: A Pathologist's View

23 citations , July 1982 in “International Journal of Dermatology”

The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.

research Traumatic Alopecia in Trichotillomania: A Pathogenic Interpretation of Histologic Lesions in the Pilosebaceous Unit

37 citations , April 1977 in “Journal of Cutaneous Pathology”

This study found that specific histologic features in skin biopsies can help support a diagnosis of traumatic alopecia (trichotillomania), but not all markers are distinct to the condition.