The HoVert Technique: A Novel Method for the Sectioning of Alopecia Biopsies

January 2011 in “ Journal of Cutaneous Pathology ”

Jennifer Nguyen, Kristin D. Hudacek, Joseph A. Whitten, Adam I. Rubin, John T. Seykora

HoVert technique scalp biopsies vertical sectioning horizontal sectioning alopecias cicatricial alopecias LPP DLE histopathological information diagnostic accuracy lichen planopilaris discoid lupus erythematosus

Studysummary This study introduces the "HoVert" technique, which generates both vertical and horizontal sections from a single biopsy to effectively differentiate lichen planopilaris from discoid lupus erythematosus in alopecia cases.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The HoVert technique, introduced as a new method for processing scalp biopsies, allows for both vertical and horizontal sectioning from a single specimen, enhancing the diagnosis of alopecias, especially cicatricial alopecias like LPP and DLE. The study applied this technique to over 20 cases, demonstrating its effectiveness in providing detailed histopathological information that improves diagnostic accuracy. The technique is praised for being simple, cost-effective, and requiring minimal additional training, while reducing the need for further biopsies. The authors concluded that the HoVert technique could be a valuable diagnostic tool for various forms of alopecia.

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Research cited in this study

6 / 6 results

research A Histologic Review of 27 Patients with Lichen Planopilaris

76 citations , June 2008 in “Journal of the American Academy of Dermatology”

In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.

research Vertical vs. Transverse Sections in Alopecia Biopsy Diagnosis

33 citations , August 2005 in “The American Journal of Dermatopathology”

This article provides departmental contact information for Dr. Dirk M. Elston at the Geisinger Medical Center and reports no research findings.

research Transverse Sections for Diagnosis of Alopecia?

24 citations , August 2005 in “The American Journal of Dermatopathology”

This article critically assesses literature favoring horizontal over vertical sections for diagnosing scalp diseases and concludes that a qualitative, vertical approach improves diagnostic precision for alopecias.

research A Comparison of Vertical Versus Transverse Sections in the Evaluation of Alopecia Biopsy Specimens

56 citations , July 2005 in “Journal of The American Academy of Dermatology”

This study found that vertical sections of alopecia biopsy specimens had a higher concordance rate with the original combined diagnosis compared to transverse sections alone, although both methods have their pros and cons.

research Vertical and Transverse Sections of Alopecia Biopsy Specimens: Combining the Two to Maximize Diagnostic Yield

71 citations , March 1995 in “Journal of The American Academy of Dermatology”

This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.