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GlossaryGenetic Loci for Patterned Hair Loss Susceptibility (GLPLS)

specific gene locations linked to increased risk of hair loss

Genetic loci for patterned hair loss susceptibility refer to specific locations on genes that are associated with an increased risk of developing patterned hair loss, such as male or female pattern baldness. These loci contain variations in DNA that can influence how likely a person is to experience hair thinning or loss, often inherited from their parents. Understanding these genetic markers helps researchers and medical professionals identify individuals at higher risk and develop targeted treatments.

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research Immunofluorescent Findings and Clinical Overlap in Two Cases of Follicular Lichen Planus

32 citations , August 1982 in “Journal of the American Academy of Dermatology”

GLPLS and LPP are variants of lichen planus.

research Graham-Little Piccardi Lassueur Syndrome and Review of the Literature

5 citations , September 2021 in “Clinical case reports”

GLPLS is a rare skin condition with specific hair loss and skin symptoms.

research Grahams Little Piccardi Lausseur Syndrome: A Rare Case Report with Literature Review

October 2023 in “International Journal of Science and Research (IJSR)”

Early diagnosis of GLPLS is crucial to prevent complications, but scarring alopecia is irreversible.

research Intralesional Injections of Triamcinolone Acetonide in the Treatment of Graham-Little Syndrome: A Case Report

December 2020 in “Forum Dermatologicum”

Intralesional triamcinolone acetonide can effectively limit the progression of GLPLS.

research Lichen Planopilaris Epidemiology: A Retrospective Study of 80 Cases

37 citations , October 2015 in “Anais Brasileiros de Dermatologia”

Lichen planopilaris mostly affects women with fair skin and can look different on each person, needing early treatment to prevent hair loss.

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community Just a friendly reminder for all! PSA

in Chat 146 upvotes 8 months ago

Avoid burning or scarring the scalp for hair growth; instead, use treatments like finasteride, minoxidil, or consider a hair transplant. Microneedling should be done carefully, and extreme methods can cause harm.

community [Theory] Big Bald is deliberately delaying the cure indefinitely

in Satire 342 upvotes 3 weeks ago

The conversation humorously suggests that the hair loss industry, referred to as "Big Bald," deliberately delays a cure to profit from ongoing treatments like minoxidil, finasteride, and dutasteride. Participants debate whether a cure would be more profitable than current treatments, with some suggesting that the industry prefers continuous treatments for sustained profit.

community Federal Grant Cuts have impacted PP405 related research

in Technology 460 upvotes 3 weeks ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.