Clinicopathologic Case 2: Multiple Intraoral White Lesions in a 55-Year-Old Female
May 2024
in “
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
”
TLDR The patient was diagnosed with oral lichen sclerosus and needs long-term monitoring.
A 55-year-old female presented with multiple intraoral white lesions and a history of psoriasis, depression, and recent hair loss. Differential diagnoses included immune-mediated disorders, genodermatoses, storage diseases, and connective tissue disorders. Histologic examination confirmed oral lichen sclerosus (LS), with further biopsies revealing cutaneous LS and alopecia areata. Management involved clobetasol and tacrolimus ointments, with follow-up recommended. LS is a rare chronic inflammatory disorder, often involving genital lesions, with potential for malignant transformation. Oral lesions should be monitored long-term by specialists. This case contributes to understanding the pathogenesis and malignant potential of oral lichen sclerosus.
