Clinicopathologic Case 2: Multiple Intraoral White Lesions in a 55-Year-Old Female
April 2024
in “
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
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Studysummary In this case report, the patient was diagnosed with oral lichen sclerosus following a detailed clinical and histological examination and referral to dermatology, and it underscores the importance of interdisciplinary collaboration in managing this rare condition and its associated risks. Our plain-language summary of this paper — not a Tressless recommendation.
A 55-year-old female presented with multiple intraoral white lesions, which were ultimately diagnosed as oral lichen sclerosus (OLS) after histological examination. The patient also had biopsy-proven lichen sclerosus on her skin and alopecia areata on her scalp. Lichen sclerosus is a rare chronic inflammatory disorder, often affecting the genital region, with potential for malignant transformation, though oral lesions have not been reported to transform into squamous cell carcinoma. The case highlights the importance of interdisciplinary collaboration for accurate diagnosis and management, involving dermatology and gynecology specialists. Treatment included clobetasol and tacrolimus ointments, with recommendations for regular follow-up to monitor for potential complications.