Clinicopathologic Case 2: Multiple Intraoral White Lesions in a 55-Year-Old Female

    April 2024 in “ Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ”
    Leen Alqudah, Yen Chen Kevin Ko, Nathan V. Lee
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    TLDR The patient was diagnosed with oral lichen sclerosus and needs long-term monitoring.
    A 55-year-old female presented with multiple intraoral white lesions, which were ultimately diagnosed as oral lichen sclerosus (OLS) after histological examination. The patient also had biopsy-proven lichen sclerosus on her skin and alopecia areata on her scalp. Lichen sclerosus is a rare chronic inflammatory disorder, often affecting the genital region, with potential for malignant transformation, though oral lesions have not been reported to transform into squamous cell carcinoma. The case highlights the importance of interdisciplinary collaboration for accurate diagnosis and management, involving dermatology and gynecology specialists. Treatment included clobetasol and tacrolimus ointments, with recommendations for regular follow-up to monitor for potential complications.
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