Lupus Around The World: Clinical And Immunological Manifestations In 151 SLE Patients Living In Dubai
January 2008
Studysummary This study suggests that Arabs with systemic lupus erythematosus in Dubai show similar clinical features to patients from other Arab and Western countries, with a notable prevalence of positive anti-Ro antibodies.
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The study examined 151 systemic lupus erythematosus (SLE) patients in Dubai, revealing a female to male ratio of 20.5:1 and a mean age of 35.5 years. The most common clinical manifestations were arthritis (88%), haematological abnormalities (61.6%), and malar rash (60.3%). Hair loss, leucopenia, fever, and proteinuria were observed in about half of the patients. Anti-nuclear antibodies were present in 98% of patients, with a high prevalence of anti-Ro antibodies (52.3%), suggesting a characteristic feature among Middle Eastern SLE patients. The study concluded that the clinical features of SLE in Dubai were similar to those in other Arab and Western countries.