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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Targeting TGFβ can improve skin immunity in older people.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

Herbal treatments can help with early-stage BPH symptoms, but more research is needed.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Human keratinocytes do not naturally respond to androgens.

Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Tiny vesicles from stem cells could be a new treatment for healing wounds.

Localized heat or specific injections can prevent chemotherapy-induced hair loss without affecting cancer treatment.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Stem cell therapy shows promise in improving burn wound healing.

Minoxidil can reduce functions related to androgen receptors.