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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Hair loss in men is common, treatable, but not curable.

Hair loss needs more research for better treatments.

Myrtle has various health benefits and potential for medicine development.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

PLD is an effective and safer alternative for treating breast cancer.

Nerves and chemicals in the body can affect hair growth and loss.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

No treatment fully prevents hair loss from chemotherapy yet.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Nanoparticle systems make cancer treatment less toxic.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.