Beyond DNA-Targeting in Cancer Chemotherapy: Emerging Frontiers - A Review

    August 2020 in “ Current topics in medicinal chemistry ”
    Simon Ngigi Mbugua, Lydia W. Njenga, Ruth A. Odhiambo, Shem O. Wandiga, Martin O. Onani
    TLDR New cancer treatments aim to reduce side effects and improve effectiveness.
    The review discussed the limitations of traditional DNA-targeting chemotherapy, which often harmed healthy rapidly dividing cells, leading to side effects like hair loss. It highlighted the need for novel cancer treatments targeting unique cellular mechanisms in cancer cells, such as nanoparticle delivery, quantum dots, metal complexes, tumor ablation, magnetic hyperthermia, pathomics, radiomics, laser surgery, and exosomes. These emerging approaches aimed to reduce toxicity and overcome cancer resistance, with detailed comparisons of their potential benefits and drawbacks. The review underscored the importance of innovative strategies in advancing cancer treatment.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Hair Loss Results After 8 Months of Dutasteride

      in Progress Pictures  232 upvotes 2 weeks ago
      The user experienced increased hair density after 8 months of using dutasteride and 6 months of oral minoxidil. Some users joked about side effects, while others discussed the effectiveness of various treatments like finasteride and rosemary oil.

      community Hair Loss Due To Chlorine and Hard Metals In Water?

      in Research/Science  1 upvotes 1 month ago
      Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

      community Hair Loss Treatments and Hair Transplant

      in Progress Pictures  4 upvotes 1 month ago
      The user is experiencing hair loss and is using oral finasteride, considering adding RU58841 and microneedling, and planning a hair transplant. They are seeking advice on whether to wait for treatment results or proceed with the transplant.

      community Hair loss steps, guide to beginners or anyone experiencing hair loss

      in Treatment  1 upvotes 1 month ago
      The conversation discusses a hair loss treatment regimen involving finasteride, dutasteride, spironolactone, bicalutamide, oral estradiol, microneedling, and minoxidil. The regimen aims to reduce androgenic alopecia by blocking DHT and androgens, with a caution about potential feminizing effects.

      community Hair loss 30F - thoughts on red light therapy vs min/fin?

      in Female  6 upvotes 1 month ago
      The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

    Similar Research

    6 / 1000+ results