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This study found that coating liquid crystalline nanoparticles with chitosan significantly enhanced the skin permeation of 5α-reductase inhibitors, suggesting a promising strategy for improving topical delivery in androgenetic alopecia treatment.

This article reviews the characteristics, diagnosis, and management of premature adrenarche and suggests it may predict future ovarian hyperandrogenism in some adolescents; no new clinical results are reported.

This study identified trilauric glyceride and decanoylcarnitine as potential biomarkers for diagnosing PCOS in patients with and without insulin resistance, suggesting significant metabolic alterations in these conditions.

This study found that in Chinese goat breeds, specific genetic variations, particularly in Tibetan Cashmere goats, are associated with traits like hair growth and adaptation to high-altitude environments.

This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

This study found that ethyl acetate extract from peanut stems demonstrated very strong antioxidant properties and moderate cytotoxic activity against MCF-7 cell lines in in-vitro and in-silico settings.

This study found that citrullinated proteins, which are implicated in rheumatoid arthritis, were abundant in outer membrane vesicles from Porphyromonas gingivalis but nearly absent in mutants, validating their approach to citrullinated peptide identification.

This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.

This study highlights the significance of the hf pathway for the skin permeation of ionized and hydrophilic high molecular compounds, and the usefulness of hf-plugging in evaluating their skin permeability.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.

This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.

In this study, transdermal application of anabolic steroids demonstrated rapid and extended detectability in urine, suggesting potential implications for doping control considerations.

This review discusses the challenges in measuring testosterone for assessing androgen excess in women and emphasizes the importance of quality control in laboratory methods, but it reports no new clinical results.

This study found that hydrophobic lipid-coated silica nanoparticles penetrated deeper into human stratum corneum compared to their hydrophilic counterparts, highlighting the influence of surface polarity on skin penetration.

Cortisol and cortisone release from hair increases in steps over time during incubation.

This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.

This review summarizes recent progress in human hair follicle bulge cell research, particularly the characterization and isolation of these stem cells, but reports no new experimental results.

This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.

This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.

This study determined that a total testosterone concentration of ≥5.1 nmol/L identified androgen-producing tumors in women with severe hyperandrogenemia, while a lower threshold of ≥2.2 nmol/L was found for diagnosing pathologic hyperandrogenism in postmenopausal women.

This study found that a commonly-used DHT enzyme immunoassay shows significant cross-reactivity with testosterone, leading to inaccurate DHT measurements compared to a gold-standard LC–MS/MS method.

This study found that a new lecithinized coal tar formulation did not stain different types of mammalian hair, suggesting it may be promising for treating scalp psoriasis without the drawback of staining.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.

This study developed a new method using liquid chromatography-tandem mass spectrometry to measure multiple steroid hormones in hair, requiring significantly fewer strands than previous methods, with high accuracy and precision.

This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.

This study used whole-genome sequence data to identify numerous putative causal variants and genes affecting key wool traits and skin wrinkle in Merino sheep, highlighting their polygenic and pleiotropic nature.

This study found that hair follicle-plugging reduced skin permeation of certain model drugs, with effects varying based on EtOH pretreatment and the drug being evaluated.