Vitamin D Receptor Ablation Alters Skin Architecture and Homeostasis of Dendritic Epidermal T Cells

    February 2005 in “ British journal of dermatology/British journal of dermatology, Supplement ”
    Simone Meindl, Antal Rot, Wolfram Hoetzenecker … Adelheid Elbe‐Bürger
    Studysummary This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.
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    Research cited in this study 9

    1. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    2. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    3. Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    4. Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    5. Metabolic And Cellular Analysis Of Alopecia In Vitamin D Receptor Knockout Mice Journal of Clinical Investigation · 2001
    6. Skin Abnormalities Generated by Temporally Controlled RXRα Mutations in Mouse Epidermis Nature · 2000
    7. Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias Archives of dermatology · 1999
    8. The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed Journal of bone and mineral research · 1998
    9. Topographical and Developmental Studies on Target Sites of 1,25 (OH)₂ Vitamin D₃ in Skin Cell & tissue research/Cell and tissue research · 1984