Skin Abnormalities Generated by Temporally Controlled RXRα Mutations in Mouse Epidermis

    October 2000 in “ Nature ”
    Mei Li, Arup Kumar Indra, Xavier Warot … Pierre Chambon
    Studysummary This study found that RXRα plays a critical role in hair cycling and keratinocyte functions in mice, likely through its interaction with VDR in epidermal cells.
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    Research cited in this study 4

    1. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    2. Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice Endocrinology · 1998
    3. Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans Experimental Dermatology · 1998
    4. Mouse Models for the Study of Human Hair Loss Dermatologic Clinics · 1996