2 citations
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April 2012 in “American Journal of Dermatopathology” Accurate diagnosis of NLS with dilated hair follicles is crucial to distinguish it from other conditions.
8 citations
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October 2012 in “Transgenic Research” The study investigated the effects of overexpressing the human H-ferritin gene in transgenic mice (hHF-tg). Two independent lines of these mice were created, both of which were viable but exhibited reduced body size compared to wild-type mice between 4-12 weeks of age. Despite normal serum iron levels and blood parameters, the hHF-tg mice experienced temporary hair loss on their trunks between 3-5 weeks of age. Histological analysis showed normal initial hair development, but during the hairless period, the mice had epidermal hyperplasia, hyperkeratosis, dilated hair follicles, bent hair shafts, and keratinous debris. The findings suggested that overexpression of the human H-ferritin gene led to mild growth retardation and a temporary hairless phenotype, highlighting the physiological roles of H-ferritin and the utility of hHF-tg mice in studying its in vivo functions.
December 2023 in “Journal of dermatology” The study concluded that key signs of Keratosis follicularis spinulosa decalvans are changes in terminal hair and vellus hair follicles, which likely start the inflammation and damage to hair follicles.
35 citations
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November 2010 in “Journal of Cutaneous Pathology” Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” The study concluded that a 'Swiss cheese' pattern in hair follicles is a useful sign for diagnosing alopecia areata.