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This study found that estrogen receptor beta plays a significant role in murine hair growth control, potentially acting as a silencer of estrogen receptor alpha's catagen-promoting effects.

Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.

This dissertation reports that horizontal basal cells in the olfactory epithelium undergo symmetric divisions balanced by population asymmetry, which supports their renewal and differentiation during tissue homeostasis and regeneration.

In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.

This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.

This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.

This study found that mice lacking REDD1 experienced an expansion of dermal white adipose tissue through both hypertrophy and hyperplasia, suggesting a potential therapeutic target for skin adipogenesis regulation.

In this study, Mpzl3-/- mice developed severe seborrhea-like dermatitis with skin inflammation, indicating MPZL3's role in the skin condition's development, independent of adaptive immunity.

This study reports the development of the first rodent model for androgenetic alopecia, demonstrating that overexpression of androgen receptors in mice delays hair regeneration and can be used to test new treatments.

This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.

This study validated the HS 3D-SeboSkin model as a reliable tool for preclinical research, effectively preserving the structure and biomarker expression of lesional and perilesional HS skin ex vivo.

In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.

This study found that grafting split-thickness human skin onto nude mice produces scars that mimic hypertrophic scar characteristics in humans, offering a useful model for studying scar formation and treatments.

In this study, researchers found that the absence of P-selectin delays inflammatory cell recruitment and reepithelialization in fetal wounds, although scar formation still occurs in later gestation wounds.

This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.

This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.

This study created a humanized mouse model of hereditary vitamin D-resistant rickets that lacks alopecia, indicating the mutant receptor's potential to explore the syndrome's characteristics beyond vitamin D binding.

This study generated FGF5-knockout Dorper sheep using the CRISPR/Cas9 system, resulting in significantly increased fine-wool and active hair-follicle density, and explored downstream signaling pathways for potential applications in androgen alopecia treatment.

In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.

This review discusses the evaluation of animal models for hair research and regeneration, highlighting their importance and limitations, and calls for improved approaches to advance understanding of human hair diseases.

This study found that OM-X® supplementation effectively prevented adverse biological changes caused by vitamin C deficiency in SMP30/GNL KO mice, improving energy maintenance, antioxidant capacity, and protein synthesis.

In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.

This study developed a transgenic mouse model to explore androgenetic alopecia, finding that inducible COX2 expression led to sebaceous gland changes and hair miniaturization, with reversible effects upon reducing COX2.

This study reported that in rat retinas under high pressure, allopregnanolone synthesis increased and helped reduce pressure-induced damage through GABAA receptors, suggesting potential therapeutic use in glaucoma.

This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.

This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.

This review discusses the use of experimental animal models to better understand the poorly understood mechanisms behind polycystic ovarian syndrome and reports no new clinical results.

This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.

This review discusses the roles of interferon-γ and PPAR-γ-mediated signalling in scarring alopecia, suggesting these pathways as potential therapeutic targets, but it reports no new empirical results.

This study successfully developed a reproducible mouse model demonstrating fetal scarless wound healing, which may provide insights for minimizing scarring in adults.