November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” This review discusses the hypotheses surrounding the developmental origins of polycystic ovary syndrome, particularly the role of prenatal androgen exposure, and reports no new experimental results.
44 citations
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May 2012 in “Endocrinology” This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.
30 citations
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August 2019 in “Medical Sciences” This review summarizes evidence suggesting that excess androgens play a key role in the origins of polycystic ovary syndrome, highlighting opportunities for developing targeted treatments.
1540 citations
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October 2008 in “Fertility and Sterility” This review discusses the definition of polycystic ovary syndrome proposed by the AE-PCOS Society Task Force, emphasizing hyperandrogenism, ovarian dysfunction, and excluding related disorders, while noting potential variations needing more research.
December 2023 in “Frontiers in endocrinology” This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.