Cutaneous Overexpression of Cyclooxygenase-2 Models Androgenetic Alopecia in Adult Mice

    Claire Hopkins, Y. H. Zheng, R. Yang … George Cotsarelis
    Studysummary This study developed a transgenic mouse model to explore androgenetic alopecia, finding that inducible COX2 expression led to sebaceous gland changes and hair miniaturization, with reversible effects upon reducing COX2.
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