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Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

Blocking mTORC1 reduces skin tumor growth in mice.

Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Meis1 is crucial for skin health and tumor development.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Touching hair can activate nearby nerve cells through signals from the hair's outer layer.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

Hair follicle stem cells can turn into various cell types and help repair nerves.