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    Nestin as a Marker of Unipotent Embryonic and Adult Progenitors Differentiating into an Epithelial Cell Lineage of the Hair Follicles

    October 2022 in “ Scientific reports ”
    Yuta Baba, Saki Onishi-Sakamoto, Kaori Ide, Koji Nishifuji
    Studysummary This study found that nestin-expressing progenitor cells, capable of becoming ORS keratinocytes, are present in both developing and adult mouse hair follicles.
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    Research cited in this study 12

    1. Progenitor Cells Expressing Nestin, a Neural Crest Stem Cell Marker, Differentiate Into Outer Root Sheath Keratinocytes Veterinary Dermatology · 2019
    2. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015
    3. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012
    4. New Insights into the Role of Runx1 in Epithelial Stem Cell Biology and Pathology Journal of Cellular Biochemistry · 2012
    5. Multipotent Nestin-Expressing Stem Cells Capable of Forming Neurons Are Located in the Upper, Middle, and Lower Part of the Vibrissa Hair Follicle Cell Cycle · 2012
    6. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    7. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    8. Chemotherapy Targets the Hair Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006
    9. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    10. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    11. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    12. Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration Journal of Investigative Dermatology · 2001

    Related research 1

    1. Alterations in the Expression of Specific Epidermal Keratin Markers in the Hairless Mouse by the Topical Application of the Tumor Promoters 2,3,7,8-Tetrachlorodibenzo-p-dioxin and the Phorbol Ester 12-O-tetradecanoylphorbol-13-acetate Carcinogenesis · 1987