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GlossaryMinoxidil (K5)

topical medication that stimulates hair growth and treats hair loss

Minoxidil, commonly known by brand names like Rogaine, is a topical medication used to treat hair loss and promote hair regrowth in conditions such as androgenetic alopecia. It works by stimulating hair follicles and increasing blood flow to the scalp, which can help to extend the growth phase of hair.

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research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter

215 citations, November 2000 in “Journal of Investigative Dermatology”

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility

189 citations, July 2009 in “The Journal of clinical investigation/The journal of clinical investigation”

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle

139 citations, December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

K6hf is a unique protein found only in a specific layer of hair follicles.

research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis

67 citations, September 2001 in “American Journal Of Pathology”

Inhibiting ODC can prevent UV-induced skin cancer.

research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration

56 citations, February 2010 in “PLOS ONE”

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

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community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 1 week ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community 5 months progress on fin and min

in Progress Pictures 1796 upvotes 1 month ago

Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

community Study published yesterday : "Brassica oleracea extract, glucosinlates and sulforaphane promote hair growth in vitro and Ex vivo"

in Research/Science 36 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically Brassica oleracea extract, glucosinolates, and sulforaphane, and their potential to promote hair growth. Users also mention minoxidil and finasteride as existing treatments.

community 3 years on Finasteride and Minoxidil. Final progress update before FUE Procedure this weekend. Updates to follow!

in Progress Pictures 376 upvotes 2 days ago

The user shared their three-year progress using finasteride and minoxidil for hair regrowth before undergoing a hair transplant procedure. They plan to continue the medication post-procedure due to its success and did not experience significant side effects.

community 21 y/o M, 3 month amazing progress on min and topical fin, I want to share my success story.

in Progress Pictures 141 upvotes 3 years ago

A 21-year-old male who has been suffering from hair loss since he was 17, and has made great progress with a combination of minoxidil and finasteride topical solutions. They discussed the efficacy of microneedling for sensitive scalps as well.

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