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    GlossaryHair Follicle Stem Cell Markers

    specific proteins identifying stem cells in hair follicles

    Hair Follicle Stem Cell Markers are specific proteins or molecules found on the surface of stem cells within hair follicles. These markers help scientists identify and isolate these stem cells, which are crucial for hair growth and regeneration. For example, markers like CD34 and K15 are commonly used to pinpoint these cells in research and therapeutic applications.

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

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      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  203 upvotes 1 week ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Keratin microspheres - breakthrough

      in Research/Science  14 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  139 upvotes 1 year ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 2 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.