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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Wnt ligands are crucial for hair growth and repair.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Applying a special compound can promote hair growth without harmful side effects.

Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.

New treatments targeting specific genes show promise for treating keratin disorders.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.