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Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Keratins are important for skin cell health and their problems can cause diseases.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Eruptive vellus hair cysts are a cosmetic skin condition, more common in young adults, with few effective treatments.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

CD98hc's role in skin health decreases with age.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.