Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein

January 1989 in “ Archives of biochemistry and biophysics ”

Patricia K. Eagon, Sandra M. Seguiti, Brian J. Rogerson, Terence F. McGuire, Lynne E. Porter, Daniel Seeley

androgen receptor androgens cytosolic androgen-binding proteins nuclear androgen-binding proteins synthetic androgen R1881 DHT dihydrotestosterone DHT metabolite male-specific estrogen binder MEB gel filtration heparin-Sepharose affinity chromatography castration testosterone pituitary gland androgen receptor androgens synthetic androgen R1881 dihydrotestosterone male-specific estrogen binder MEB testosterone pituitary gland

Studysummary This study found that androgen binding in male rat livers involves specific androgen receptors, which decrease with castration and are inducible in female livers with testosterone.

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