24 citations
,
January 1989 in “Archives of biochemistry and biophysics” This study found that androgen binding in male rat livers involves specific androgen receptors, which decrease with castration and are inducible in female livers with testosterone.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.
72 citations
,
January 2003 in “American Journal of Pathology” This study found that the co-activator CBP enhances the agonistic action of hydroxyflutamide on androgen receptors, suggesting a mechanism for therapy resistance in prostate cancer.
20 citations
,
January 2019 in “Journal of dermatological science” This study suggests that androgens enhance growth factor production in dermal fibroblasts, which in turn may alter keratinocyte differentiation and contribute to acne lesion formation.
1 citations
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study uses cryo-electron microscopy to reveal how androgen receptor forms a non-obligate dimer to bind DNA, with implications for prostate cancer development.