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    Glossary Interfollicular Epidermis

    outer skin layer between hair follicles

    The interfollicular epidermis is the part of the skin's outer layer that exists between hair follicles. It plays a crucial role in protecting the body from environmental damage, preventing water loss, and serving as a barrier against pathogens. This area is composed of multiple layers of cells, including keratinocytes, which are responsible for producing keratin, a protein that strengthens the skin.

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    Research 30 of 1000+

    1. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    2. α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis Journal of Cell Science · 2003 · 45 citations
    3. Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis Stem Cell Research & Therapy · 2015 · 14 citations
    4. Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis Journal of Investigative Dermatology · 2004 · 10 citations
    5. Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis Genes · 2020 · 7 citations
    6. Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide Journal of Investigative Dermatology · 2007 · 2 citations
    7. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    8. Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration International Journal of Molecular Sciences · 2026
    9. 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor Journal of Investigative Dermatology · 2022
    10. 1337 Single cell transcriptome profiling of human interfollicular epidermis reveals robust heterogeneity and divergent differentiation lineages Journal of Investigative Dermatology · 2018
    11. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    12. Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    13. [Development of interfollicular epidermis on the surface of collagen framework of the dermis in experimental animals]. PubMed · 1992
    14. LB1019 The early region of trichodysplasia spinulosa polyomavirus drives proliferation, altered differentiation, and ectopic expression of hair follicle differentiation markers in interfollicular tail epidermis 2022
    15. The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse Virchows Archiv B Cell Pathology · 1977 · 23 citations
    16. Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis 2017
    17. Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · 1975 · 34 citations
    18. WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation Journal of Investigative Dermatology · 2013 · 18 citations
    19. The arrector pili muscle, the bridge between the follicular stem cell niche and the interfollicular epidermis Anatomical Science International · 2016 · 14 citations
    20. Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments Histochemistry and Cell Biology · 2010 · 28 citations
    21. Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice Acta histochemica · 2012 · 11 citations
    22. Toxicological Responses in Keratinocyte Interfollicular Stem Cells 2018
    23. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009 · 503 citations
    24. Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis Development · 2003 · 421 citations
    25. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    26. Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours Development · 2002 · 297 citations
    27. Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Proceedings of the National Academy of Sciences · 2001 · 201 citations
    28. Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis Journal of Investigative Dermatology · 2007 · 78 citations
    29. Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells Molecular biology of the cell · 2008 · 43 citations
    30. Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three‐dimensional skin equivalent model <i>in vitro</i>: implications for regenerative therapy of canine epidermis Veterinary dermatology · 2013 · 11 citations